Plastic pollution is everywhere—from our oceans to our bodies, even our blood. Each year, people may ingest up to 50 plastic bags’ worth of microplastics through food and water. This November, the UN has a historic chance to address this crisis by negotiating a global treaty to end plastic pollution. The treaty must be ambitious, enforceable, and equitable, tackling the issue from production to disposal. With public demand for change surging, the time for action is now. Let’s ensure that this opportunity is not wasted—for the planet and for future generations.